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For example, drugs like chlorpromazine can turn off the "voices" heard by some people with psychosis and help them to see reality more clearly.

And antidepressants can lift the dark, heavy moods of depression.

The National Institute of Mental Health, other Federal agencies, and private research groups are sponsoring studies of these medications.

Scientists are hoping to improve their understanding of how and why these medications work, how to control or eliminate unwanted side effects, and how to make the medications more effective.

The degree of response--ranging from a little relief of symptoms to complete relief--depends on a variety of factors related to the individual and the disorder being treated.